Publication
Title
Why target immune cells for plasma treatment of cancer
Author
Abstract
This paper addresses the challenge of using non-equilibrium plasma as a therapeutic approach for diseases of body systems not readily accessible to plasma-generated factors. The role of plasma stimulation of the immune system is discussed as a conceivable mechanism to deliver effects. This is especially important for treatment of cancers since the pathogenesis and progression of cancers are directly influenced by immune function. By optimizing plasma parameters to induce immunogenic cell death in tumors locally, it is possible to trigger specific, protective immune responses systemically. The observations from in vitro and in vivo investigations on this subject are reviewed here. An in depth understanding of the interaction between plasma components and the cells of the immune system may provide necessary information for use of plasmas in treatment of many systemic diseases. The clinical implications of treating cancers with non-equilibrium plasma are considered. The paper also identifies some hurdles that must be overcome before plasma immunotherapy becomes a clinical reality.
Language
English
Source (journal)
Plasma chemistry and plasma processing. - New York
Source (book)
22nd International Symposium on Plasma Chemistry (ISPC 22), July 05-10, 2015, Antwerp, Belgium
Publication
New York : 2016
ISSN
0272-4324
Volume/pages
36 :1 (2016) , p. 259-268
ISI
000370720800015
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 12.12.2018
Last edited 25.08.2021