Publication
Title
MDSCs in infectious diseases : regulation, roles, and readjustment
Author
Abstract
Many pathogens, ranging from viruses to multicellular parasites, promote expansion of MDSCs, which are myeloid cells that exhibit immunosuppressive features. The roles of MDSCs in infection depend on the class and virulence mechanisms of the pathogen, the stage of the disease, and the pathology associated with the infection. This work compiles evidence supported by functional assays on the roles of different subsets of MDSCs in acute and chronic infections, including pathogen-associated malignancies, and discusses strategies to modulate MDSC dynamics to benefit the host.
Language
English
Source (journal)
Cancer immunology and immunotherapy. - Heidelberg
Cancer immunology and immunotherapy. - Heidelberg
Publication
Heidelberg : 2019
ISSN
0340-7004 [print]
1432-0851 [online]
Volume/pages
68 :4 (2019) , p. 673-685
ISI
000463762200014
Pubmed ID
30569204
Full text (Publisher's DOI)
Full text (open access)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Project info
Mechanism of infection of sialoadhesin (Sn)-positive macrophages with respiratory syncytial virus (RSV) and its implications for inflammation and immune pathology during bronchiolitis.
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 20.12.2018
Last edited 21.10.2021
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