Publication
Title
To NET or not to NET : current opinions and state of the science regarding the formation of neutrophil extracellular traps
Author
Abstract
Since the discovery and definition of neutrophil extracellular traps (NETs) 14 years ago, numerous characteristics and physiological functions of NETs have been uncovered. Nowadays, the field continues to expand and novel mechanisms that orchestrate formation of NETs, their previously unknown properties, and novel implications in disease continue to emerge. The abundance of available data has also led to some confusion in the NET research community due to contradictory results and divergent scientific concepts, such as pro- and anti-inflammatory roles in pathologic conditions, demarcation from other forms of cell death, or the origin of the DNA that forms the NET scaffold. Here, we present prevailing concepts and state of the science in NET-related research and elaborate on open questions and areas of dispute.
Language
English
Source (journal)
Cell death and differentiation. - Oxford
Cell death and differentiation. - Oxford
Publication
London : Nature publishing group , 2019
ISSN
1350-9047
Volume/pages
26 :3 (2019) , p. 395-408
ISI
000458012500001
Pubmed ID
30622307
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 15.01.2019
Last edited 21.10.2021
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