Title
|
|
|
|
Ewing's sarcoma and primary osseous lymphoma : spectrum of imaging appearances
|
|
Author
|
|
|
|
|
|
Abstract
|
|
|
|
Ewing's sarcoma (ES) is a rare, highly malignant anaplastic stem cell tumor. Histologically, the tumor consists of uniform densely packed small monomorphic cells with round nuclei. The typical appearance at hematoxylin and eosin (H&E) staining is small blue round cells without any matrix formation. On conventional radiography, ES typically presents as a permeative lesion in the diaphysis of a long bone in a child. A large soft tissue component is another characteristic feature, best depicted by magnetic resonance imaging. Primary osseous lymphomas are most commonly highly malignant B-cell lymphomas. At H&E histologic staining, the tumor stroma consists of diffuse round-cell infiltrates that resembles the appearance of ES. Although there is no typical imaging appearance of an osseous lymphoma, it should be considered in an adult presenting with a Lodwick grade II or III lesion in the metaphysis or diaphysis of a large long bone, the pelvis, or the vertebral column. Histologic confirmation is mandatory. |
|
|
Language
|
|
|
|
English
|
|
Source (journal)
|
|
|
|
Seminars in musculoskeletal radiology
|
|
Publication
|
|
|
|
2019
|
|
ISSN
|
|
|
|
1089-7860
|
|
DOI
|
|
|
|
10.1055/S-0038-1676125
|
|
Volume/pages
|
|
|
|
23
:1
(2019)
, p. 36-57
|
|
ISI
|
|
|
|
000458980000005
|
|
Pubmed ID
|
|
|
|
30699452
|
|
Full text (Publisher's DOI)
|
|
|
|
|
|
Full text (open access)
|
|
|
|
|
|
Full text (publisher's version - intranet only)
|
|
|
|
|
|