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Title
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Ewing's sarcoma and primary osseous lymphoma : spectrum of imaging appearances
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Author
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Abstract
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| Ewing's sarcoma (ES) is a rare, highly malignant anaplastic stem cell tumor. Histologically, the tumor consists of uniform densely packed small monomorphic cells with round nuclei. The typical appearance at hematoxylin and eosin (H&E) staining is small blue round cells without any matrix formation. On conventional radiography, ES typically presents as a permeative lesion in the diaphysis of a long bone in a child. A large soft tissue component is another characteristic feature, best depicted by magnetic resonance imaging. Primary osseous lymphomas are most commonly highly malignant B-cell lymphomas. At H&E histologic staining, the tumor stroma consists of diffuse round-cell infiltrates that resembles the appearance of ES. Although there is no typical imaging appearance of an osseous lymphoma, it should be considered in an adult presenting with a Lodwick grade II or III lesion in the metaphysis or diaphysis of a large long bone, the pelvis, or the vertebral column. Histologic confirmation is mandatory. |
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Language
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English
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Source (journal)
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Seminars in musculoskeletal radiology
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Publication
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2019
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ISSN
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1089-7860
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DOI
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10.1055/S-0038-1676125
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Volume/pages
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23
:1
(2019)
, p. 36-57
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ISI
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000458980000005
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Pubmed ID
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30699452
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Full text (Publisher's DOI)
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Full text (open access)
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Full text (publisher's version - intranet only)
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