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Title
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Ultrasound assessment of rectus femoris muscle in rehabilitation patients with chronic obstructive pulmonary disease screened for sarcopenia : correlation of muscle size with quadriceps strength and fat-free mass
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Author
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Abstract
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| PurposeTo determine the relationship of the size of the rectus femoris muscle, assessed by ultrasonography, with parameters of muscle strength and body composition that are commonly used in the case-finding of sarcopenia in rehabilitation patients with chronic obstructive pulmonary disease (COPD).MethodsCross-sectional pilot study of 18 men with severe COPD and 17 healthy controls. Main outcome variables: cross-sectional area, thickness, and width of the non-dominant rectus femoris muscle obtained by ultrasound, muscle strength determined by voluntary maximum isometric contraction of the quadriceps muscle, and fat-free mass assessed by bioimpedance analysis.ResultsUltrasounds detected differences in the size of the rectus femoris muscle: cross-sectional area was 4.3 (SD 1.05) cm(2) in patients, compared to 5.6 (SD 1.25) cm(2) in controls; patients also presented lower quadriceps strength, and fat-free mass index. Cross-sectional area of the rectus femoris muscle showed a moderate correlation with quadriceps strength (R=0.497, p=0.036) and fat-free mass (R=0.584, p=0.011). In a multivariate linear model adjusted for age, body mass index,fat-free mass and muscle size, muscle strength was 7.44kg lower (p value=0.014) in patients, compared to controls.ConclusionsA causal relationship was observed between the cross-sectional area of the rectus femoris muscle, assessed with ultrasonography, and maximum isometric strength of knee extension in COPD rehabilitation patients. Reduced cross-sectional area was also associated with loss of fat-free mass. Muscle ultrasound and bioimpedance analysis provide complementary and relevant information that could be useful in the case-finding of sarcopenia in COPD patients. |
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Language
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English
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Source (journal)
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European geriatric medicine / European Union Geriatric Medicine Society. - Amsterdam, 2010, currens
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Publication
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Amsterdam
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Elsevier
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2019
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ISSN
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1878-7649
[print]
1878-7657
[online]
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DOI
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10.1007/S41999-018-0130-7
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Volume/pages
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10
:1
(2019)
, p. 89-97
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ISI
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000457150600011
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Full text (Publisher's DOI)
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Full text (publisher's version - intranet only)
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