Publication
Title
Carbamate synthesis via a shelf stable and renewable C1 reactant
Author
Abstract
4‐Propylcatechol carbonate is a shelf‐stable, renewable C1 reactant. It is easily prepared from renewable 4‐propylcatechol (derived from wood) and dimethyl carbonate (derived from CO2) using a reactive distillation system. In this work the carbonate reactant has been used for the two‐step synthesis of carbamates under mild reaction conditions. In the first step, 4‐propylcatechol carbonate is reacted with an alcohol at 50‐80 °C using a Lewis acid catalyst (e.g. Zn(OAc)2.2H2O). With liquid alcohols no solvent and with solid alcohols 2‐methyltetrahydrofuran was used as solvent. In the second step, the alkyl 2‐hydroxy‐propylphenyl carbonates intermediates obtained are reacted with amines at room temperature in 2‐methyltetrahydrofuran, forming the target carbamates and by‐product 4‐propylcatechol, which can be recycled into carbonate reactant.
Language
English
Source (journal)
Chemsuschem. - Weinheim
Publication
Weinheim : 2019
ISSN
1864-5631
DOI
10.1002/CSSC.201900406
Volume/pages
12 :13 (2019) , p. 3103-3114
ISI
000477706600035
Pubmed ID
30921504
Full text (Publisher's DOI)
Full text (open access)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Project info
Partial replacement of the NMR infrastructure for the structural elucidation of synthetic and natural substances.
Synthesis of a-secondary alkylamines via reductive functionalization of amides.
Bio based factory: Sustainable chemistry from wood (BioFact).
Development and use of "smart" and sustainable phosgene analogues.
Biorefinery of entire plant biomass to aromatics (ARBOREF).
BIO-HArT (Biorizon Innovative and Scale up of Renewable Aromatics Technology)
Sustainable reduction reactions in water via in situ hydrogen gas production.
CalcUA as central calculation facility: supporting core facilities.
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identifier
Creation 01.04.2019
Last edited 02.10.2024
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