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Title
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Antibiofilm activity of polyamide 11 modified with thermally stable polymeric biocide polyhexamethylene guanidine 2-naphtalenesulfonate
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Author
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Abstract
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| The choice of efficient antimicrobial additives for polyamide resins is very difficult because of their high processing temperatures of up to 300 degrees C. In this study, a new, thermally stable polymeric biocide, polyhexamethylene guanidine 2-naphtalenesulfonate (PHMG-NS), was synthesised. According to thermogravimetric analysis, PHMG-NS has a thermal degradation point of 357 degrees C, confirming its potential use in joint melt processing with polyamide resins. Polyamide 11 (PA-11) films containing 5, 7 and 10 wt% of PHMG-NS were prepared by compression molding and subsequently characterised by FTIR spectroscopy. The surface properties were evaluated both by contact angle, and contactless induction. The incorporation of 10 wt% of PHMG-NS into PA-11 films was found to increase the positive surface charge density by almost two orders of magnitude. PA-11/PHMG-NS composites were found to have a thermal decomposition point at about 400 degrees C. Mechanical testing showed no change of the tensile strength of polyamide films containing PHMG-NS up to 7 wt%. Antibiofilm activity against the opportunistic bacteria Staphylococcus aureus and Escherichia coli was demonstrated for films containing 7 or 10 wt% of PHMG-NS, through a local biocide effect possibly based on an influence on the bacterial eDNA. The biocide hardly leached from the PA-11 matrix into water, at a rate of less than 1% from its total content for 21 days. |
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Language
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English
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Source (journal)
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International journal of molecular sciences
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Publication
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2019
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ISSN
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1422-0067
1661-6596
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DOI
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10.3390/IJMS20020348
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Volume/pages
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20
:2
(2019)
, 19 p.
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Article Reference
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348
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ISI
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000459746500116
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Pubmed ID
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30654458
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Medium
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E-only publicatie
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Full text (Publisher's DOI)
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Full text (open access)
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