|
Title
|
|
|
|
Cannabis allergy : what the clinician needs to know in 2019
|
|
|
Author
|
|
|
|
|
|
|
Abstract
|
|
|
|
| Introduction: Although the use of cannabis dates back millennia, the first description of cannabis allergy is relatively recent (1971). Recent large-scale data show that cannabis allergy can manifest severe and generalized symptoms with extensive cross-reactions. Thus, it is essential to become familiarized with its clinical presentation, diagnostic aids, and adequate therapeutic guidance. Areas covered: Here we provide a hands-on overview on cannabis allergy focusing on symptomatology and the reliability of diagnostic options. Recent advances in proteomics are discussed in detail, elucidating the link with nsLTP-related allergies. The proteomics advancements have paved the way for more reliable diagnostics, especially component-based tools. Finally, the current experience in treatment options is highlighted. Expert opinion: Cannabis allergy is an allergy entity which can significantly impact the quality of life. For optimal diagnosis, we advise to start with a validated and standardized crude-extract based test such as sIgE hemp complemented by component-based diagnostics such as sIgE Can s 3 quantifications where available. Future research should lift the veil on the true prevalence of cannabis allergy and the importance of other cannabis allergens to further guide our practice. |
|
|
|
Language
|
|
|
|
English
|
|
|
Source (journal)
|
|
|
|
Expert review of clinical immunology
|
|
|
Publication
|
|
|
|
2019
|
|
|
ISSN
|
|
|
|
1744-666X
1744-8409
|
|
|
DOI
|
|
|
|
10.1080/1744666X.2019.1600403
|
|
|
Volume/pages
|
|
|
|
15
:6
(2019)
, p. 599-606
|
|
|
ISI
|
|
|
|
000468394400003
|
|
|
Pubmed ID
|
|
|
|
30946607
|
|
|
Full text (Publisher's DOI)
|
|
|
|
|
|
|
Full text (open access)
|
|
|
|
|
|
|
Full text (publisher's version - intranet only)
|
|
|
|
|
|