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Title
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Scoring of hypersomnolence and fatigue in patients with obstructive sleep apnea treated with a titratable custom-made mandibular advancement device
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Author
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Abstract
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| Study Objectives: The objective of this study was to measure fatigue and hypersomnolence in patients with obstructive sleep apnea (OSA) treated with a mandibular advancement device (MAD), using Epworth Sleepiness Scale (ESS) for hypersomnolence and Checklist Individual Strength questionnaire (CIS20R) for fatigue. Methods: This was a single-center, prospective cohort study. A total of 58 patients with OSA filled out ESS and CIS20R questionnaires at baseline and after 3 months of MAD treatment. A total of 39 full datasets were collected. Statistical analysis for reliability of the questionnaires, comparison between baseline and 3-month follow-up, correlation between the changes in the values of the two questionnaires, and changes in apnea-hypopnea index (AHI) were performed. Results: CIS20R showed excellent reliability in this patient group at baseline and 3-month follow-up (Cronbach alpha = .97), ESS showed a marginally good reliability (Cronbach alpha = .82). The CIS20R (82/140) expressed high levels of fatigue at baseline, and ESS showed a normal level of daytime sleepiness. AHI, ESS, and CIS20R were significantly reduced under MAD treatment. A significant correlation between ESS and CIS20R was observed. No significant correlation between any of the questionnaires and the change in AHI was found. Conclusions: The CIS20R questionnaire results showed a high level of fatigue in the patients with OSA, and the questionnaire can be used to evaluate changes in fatigue due to MAD treatment after 3 months. The ESS failed to show similar characteristics. Therefore, a combination of ESS for hypersomnolence with CIS20R for fatigue is proposed for the follow-up of patients with OSA treated with MAD. |
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Language
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English
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Source (journal)
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Journal of clinical sleep medicine
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Publication
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2019
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ISSN
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1550-9389
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DOI
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10.5664/JCSM.7728
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Volume/pages
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15
:4
(2019)
, p. 623-628
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Article Reference
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PII jc-18-00563
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ISI
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000464568000013
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Pubmed ID
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30952225
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Medium
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E-only publicatie
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Full text (Publisher's DOI)
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