Title
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Selenium status in elderly people : longevity and age-related diseases
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Author
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Abstract
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Background: Selenium (Se) is a trace element active in selenoproteins, which can regulate oxidative stress. It is generally perceived as an import factor for maintaining health in the elderly. Methods: The goal of this review is to discuss selenium concentration in biological samples, primarily serum or plasma, as a function of age and its relation with longevity. The elemental level in various age-related diseases is reviewed. Conclusion: Highest selenium values were observed in healthy adults, while in an elderly population significantly lower concentrations were reported. Variables responsible for contradictory findings are mentioned. Risk and benefits of Se-supplementation still remain under debate. |
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Language
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English
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Source (journal)
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Current pharmaceutical design. - Schiphol, 1995, currens
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Publication
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Sharjah
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Bentham science publ ltd
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2019
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ISSN
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1381-6128
[print]
1873-4286
[online]
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DOI
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10.2174/1381612825666190701144709
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Volume/pages
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25
:15
(2019)
, p. 1694-1706
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ISI
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000481642500003
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Pubmed ID
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31267854
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Full text (Publisher's DOI)
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Full text (open access)
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