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Title
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Image-guided conformation arc therapy for prostate cancer: Early side effects
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Author
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Abstract
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| Purpose: To evaluate early side effects in prostate cancer patients treated with image-guided conformation arc therapy (IGCAT) using a minimultileaf collimator and daily X-ray-assisted patient positioning. Methods and Materials: Between May 2000 and November 2004, 238 cT1-T3N0M0 tumors were treated with doses of 70 or 78 Gy. Seventy patients also received neoadjuvant or concurrent hormonal treatment. Median follow-up is 18 months (range, 4-55 months). The Radiation Therapy Oncology Group and the European Organization for Research and Treatment of Cancer toxicity scoring system was used to evaluate early side effects. Results: Grade 1, 2, and > 2 acute side effects occurred in 19, 6, and 0% (gastrointestinal) and 37, 16, and 0% (genitourinary) of the patients. No relation between radiation dose and early side effects was observed. Conclusion: Patients treated with image-guided conformation arc therapy experience a low rate of Grade 2 (i.e., requiring medication) early side effects. The definitive evaluation of late side effects and biochemical control requires further follow-up. (c) 2006 Elsevier Inc. |
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Language
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English
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Source (journal)
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International journal of radiation oncology, biology, physics. - Bedford
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Publication
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Bedford
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2006
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ISSN
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0360-3016
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DOI
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10.1016/J.IJROBP.2006.05.077
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Volume/pages
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66
:4s:[S]
(2006)
, p. S141-S144
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ISI
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000241738400024
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Full text (Publisher's DOI)
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