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Title
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The use of household cleaning products during pregnancy and lower respiratory tract infections and wheezing during early life
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Author
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Abstract
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| To evaluate the effects of household use of cleaning products during pregnancy on infant wheezing and lower respiratory tract infections (LRTI). In four prospective Spanish birth cohorts (n = 2,292), pregnant women reported the use of household cleaning products. When infants were 12-18 months old, current cleaning product use and infant's wheezing and LRTI were reported. Cohort-specific associations between the use of specific products and respiratory outcomes were evaluated using multivariable regression analyses and estimates were combined using random-effects meta-analyses. The period prevalence of LRTI was higher when sprays (combined odds ratio (OR) = 1.29; 95 % confidence interval (CI) 1.04-1.59) or air fresheners (OR = 1.29; CI 1.03-1.63) were used during pregnancy. The odds of wheezing increased with spray (OR = 1.37; CI 1.10-1.69) and solvent (OR = 1.30; CI 1.03-1.62) use. The associations between spray and air freshener use during pregnancy and both outcomes remained apparent when these products were not used after pregnancy. Nevertheless, the estimates were higher when post-natal exposure was included. The use of cleaning sprays, air fresheners and solvents during pregnancy may increase the risk of wheezing and infections in the offspring. |
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Language
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English
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Source (journal)
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International journal of public health. - Berlin, 2007, currens
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Publication
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Berlin
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2013
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ISSN
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1661-8556
[print]
1661-8564
[online]
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DOI
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10.1007/S00038-012-0417-2
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Volume/pages
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58
:5
(2013)
, p. 757-764
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ISI
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000325013000012
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Pubmed ID
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23064260
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Full text (Publisher's DOI)
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