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Title
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Adoptive cell transfer of regulatory T cells exacerbates hepatic steatosis in high-fat high-fructose diet-fed mice
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Author
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Abstract
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| Non-alcoholic steatohepatitis (NASH) is a multisystem condition, involving the liver, adipose tissue, and immune system. Regulatory T (Treg) cells are a subset of T cells that exert an immune-controlling effect. Previously, a reduction of Treg cells in the visceral adipose tissue (VAT) was shown to be associated with a more severe degree of liver disease. We aimed to correct this immune disruption through adoptive cell transfer (ACT) of Treg cells. |
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Language
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English
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Source (journal)
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Frontiers in immunology. - Place of publication unknown
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Publication
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Place of publication unknown
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2020
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ISSN
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1664-3224
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DOI
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10.3389/FIMMU.2020.01711
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Volume/pages
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11
(2020)
, 10 p.
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Article Reference
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1711
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ISI
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000561556400001
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Pubmed ID
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32849604
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Medium
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E-only publicatie
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Full text (Publisher's DOI)
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Full text (open access)
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