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Title
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Histopathological findings in the advanced natural evolution of the SARS-CoV-2 infection
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Author
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Abstract
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| We are reporting a case of natural evolution and pathological data from a young person that was diagnosed with coronavirus disease 2019 (COVID-19). All data has been collected from the autopsy of a 30-year-old female, which was performed by the Department of Forensic Medicine from Emergency County Hospital, Drobeta Turnu Severin, Mehedinti County, Romania. The infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was confirmed by reverse transcription polymerase chain reaction (RT-PCR) on the lung tissue which was obtained during autopsy. This case provides the opportunity to study the natural evolution of COVID-19 pneumonia in a young person with clinical signs of pneumonia but without associated comorbidities. The patient had not received any treatment. The histopathological examination of the lung revealed a process of productive proliferation, proteinaceous and fibrin-macrophagic interalveolar spaces exudate, and lesions consistent with vasculitis. In the heart, we identified a cardiac thrombus. These changes are likely to suggest an advanced natural evolution of SARS-CoV-2 virus infection. |
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Language
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English
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Source (journal)
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Romanian journal of morphology and embryologie / Societatea Română de Morfologie. - Bucureşti, 1990, currens
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Publication
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Bucureşti
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Editura Academiei Române
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2020
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ISSN
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1220-0522
[print]
2066-8279
[online]
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DOI
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10.47162/RJME.61.1.23
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Volume/pages
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61
:1
(2020)
, p. 209-218
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ISI
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000559108700001
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Pubmed ID
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32747912
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Full text (Publisher's DOI)
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Full text (open access)
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