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Title
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In Vivo imaging in rodents
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Author
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Abstract
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| In vivo imaging is increasingly used in combination with animal models of epilepsy because of the multifaceted information that can be obtained using different imaging modalities. Here we describe the basis of different magnetic resonance imaging methods and nuclear imaging techniques, such as positron emission and single photon emission computer tomography. We provide examples to demonstrate their key application areas in experimental epilepsy research, and give practical guidelines for implementation. Together these techniques can be applied to visualize structural, metabolic, and functional changes in longitudinal study designs to provide unique information about disease progression and potentially translatable biomarkers for epileptogenesis and epilepsy. |
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Language
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English
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Source (book)
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Models of seizures and epilepsy / Pitkänen, Asla [edit.]; et al. [edit.]
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Publication
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Elsevier Inc.
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2017
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ISBN
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978-0-12-804066-9
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DOI
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10.1016/B978-0-12-804066-9.00014-6
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Volume/pages
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p. 197-215
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Edition
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2de
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Full text (Publisher's DOI)
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