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Title
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Surfactant use in late preterm infants : a survey among Belgian neonatologists
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Author
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Abstract
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| Specific recommendations on surfactant administration in late preterm (LPT) infants with pulmonary disease are lacking. We performed an online-based, nationwide survey amongst all (n= 102) Belgian neonatologists to identify the use of surfactant in LPT infants suffering from several respiratory pathologies. The survey used clearly defined clinical cases and resulted in a 86% response rate. Neonatologists adhere to the 200 mg/kg initial surfactant dosing scheme. Surfactant is widely used in respiratory distress syndrome (70.1%), but there is less unanimity on its use in meconium aspiration syndrome (58.0%), transient tachypnoea of the newborn (30.6%), congenital pneumonia (27.2%) and congenital diaphragmatic hernia (8.6%). Respondents adhere to the European guideline of a timely referral to a newborn intensive care unit (non-invasive ventilation and FiO(2)> 0.30 at 12 h of age), in order to minimise the risk of deterioration. Conclusion: We demonstrate a wide variety in the use of surfactant within LPT infants. The majority of Belgian neonatologists therefore urge for an investment in multi-centre trials on surfactant administration in LPT infants, in order to create an evidence-based practice as well as to reduce the strain on health care budgets. What is Known: Any late preterm (LPT) infant with respiratory distress needs a timely referral to a neonatal intensive care unit in case of non-invasive ventilation and FiO(2)> 0.30 at 12 h of life, in order to minimise the risk of acute deterioration as well as chronic lung disease. Any modest increase in morbidity in the sizeable group of LPT infants exerts a significant strain on health care budgets. What is New: We report the attitudes and opinions of Belgian neonatologists about the use of surfactant in LPT infants suffering from several respiratory diseases. Our survey demonstrates a significant variability in practice between neonatologists during treatment of respiratory pathologies in LPT infants. This highlights an urgent need for univocal therapeutic lines. |
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Language
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English
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Source (journal)
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European journal of pediatrics. - Berlin, 1975, currens
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Publication
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New york
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Springer
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2021
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ISSN
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0340-6199
[print]
1432-1076
[online]
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DOI
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10.1007/S00431-020-03806-1
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Volume/pages
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180
(2021)
, p. 885-892
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ISI
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000572589900001
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Pubmed ID
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32970243
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Full text (Publisher's DOI)
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Full text (publisher's version - intranet only)
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