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Title
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Muscle wasting after coronary artery bypass graft surgery : impact on post-operative clinical status and effect of exercise-based rehabilitation
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Author
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Abstract
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| Background:Coronary artery bypass graft (CABG) surgery is known to induce significant muscle wasting. It remains to be investigated whether muscle wasting after CABG surgery relates to a worse clinical status at entry of rehabilitation and exercise-based rehabilitation remediates such muscle wasting. Design:Prospective observational study. Methods:In 21 males, changes in lean tissue mass (LTM) after CABG surgery were assessed and during a 12-week endurance exercise-based rehabilitation intervention. Changes in blood parameters and cardiopulmonary exercise capacity were assessed, and relations with changes in LTM were analysed. Results:LTM decreased by -1.9 +/- 2.5 kg (p < .05) within 3 weeks after CABG surgery: greater LTM loss related to a lower ventilatory threshold at entry of rehabilitation (r = 0.58-0.61,p < .05). LTM was fully restored (+2.1 +/- 2.4 kg,p < .05) during rehabilitation. Conclusion:In males, CABG-induced LTM reduction was associated with a worse aerobic exercise tolerance at entry of rehabilitation, but this LTM reduction was fully remediated by endurance exercise-based rehabilitation. |
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Language
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English
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Source (journal)
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Acta cardiologica. - Bruxelles
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Publication
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Bruxelles
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2020
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ISSN
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0001-5385
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DOI
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10.1080/00015385.2019.1598035
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Volume/pages
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75
:5
(2020)
, p. 406-410
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ISI
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000575195300004
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Pubmed ID
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31057075
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Full text (Publisher's DOI)
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Full text (open access)
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