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Title
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Modelling of a nutrient feedback mechanism during human digestion of carbohydrates
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Author
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Abstract
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| The paper builds on previous work (Moxon et al. 2016), to add a nutrient based feedback mechanism to a model of gastric and intestinal nutrient transport during human digestion. The mechanism operates as an ‘on-off’ switch, whereby if the maximum absorption rate is reached, the gastric emptying rate is set to zero. The model parameters were estimated against in vivo results from literature, followed by a Monte Carlo simulation to see how the parameter estimates are affected by the random noise in the experimental data, where the parameter estimates for high viscosity solutions show more sensitivity to experimental noise. A sensitivity analysis on the gastric content showed that the system is most sensitive to changes in parameters when high glucose, high viscosity liquids are consumed. |
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Language
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English
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Source (book)
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Proceedings of FOODSIM 2016, 3-7 April, 2016, Ghent, Belgium
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Publication
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Eurosis
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2016
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ISBN
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978-90-77381-92-2
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Volume/pages
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p. 53-57
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