Title
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X-ray phase contrast simulation for grating-based interferometry using GATE
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Author
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Abstract
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The overall importance of x-ray phase contrast (XPC) imaging has grown substantially in the last decades, in particular with the recent advent of compact lab-based XPC systems. For optimizing the experimental XPC setup, as well as benchmarking and testing new acquisition and reconstruction techniques, Monte Carlo (MC) simulations are a valuable tool. GATE, an open source application layer on top of the Geant4 simulation software, is a versatile MC tool primarily intended for various types of medical imaging simulations. To our knowledge, however, there is no GATE-based academic simulation software available for XPC imaging. In this paper, we extend the GATE framework with new physics-based tools for accurate XPC simulations. Our approach combines Monte Carlo simulations in GATE for modelling the x-ray interactions in the sample with subsequent numerical wave propagation, starting from the GATE output. |
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Language
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English
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Source (journal)
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Optics express. - -
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Publication
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2020
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ISSN
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1094-4087
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DOI
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10.1364/OE.392337
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Volume/pages
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28
:22
(2020)
, p. 33390-33412
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ISI
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000582499400090
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Pubmed ID
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33115004
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Full text (Publisher's DOI)
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Full text (open access)
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