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Title
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Electroactivity of superoxide anion in aqueous phosphate buffers analyzed with platinized microelectrodes
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Author
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Abstract
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| The reactivity of platinized ultramicroelectrodes (Pt-black UMEs) towards superoxide anion O-2(.-), an unstable Reactive Oxygen Species (ROS), and its relatives, H2O2 and O-2, was studied. Voltammetric studies in PBS demonstrate that Pt-black UMEs provide: i) a well-resolved reversible redox signature for O-2(.-) detected in both alkaline and physiological buffers (pH 12 and 7.4); ii) irreversible oxidation and reduction waves for H2O2 at pH 7.4. The oxygen reduction reaction (ORR) at Pt-black surfaces solely yields H2O2 (2 electrons/2 H+) at physiological pH. Consequently, Pt-black UMEs allow to sense different ROS including superoxide anion for future biomedical or physico-chemical investigations. |
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Language
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English
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Source (journal)
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Electroanalysis. - Deerfield Beach, Fla
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Publication
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Weinheim
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Wiley-v c h verlag gmbh
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2021
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ISSN
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1040-0397
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DOI
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10.1002/ELAN.202060456
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Volume/pages
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33
:4
(2021)
, p. 882-890
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ISI
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000590291800001
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Full text (Publisher's DOI)
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Full text (open access)
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Full text (publisher's version - intranet only)
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