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Title
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Association between the histopathological growth patterns of liver metastases and survival after hepatic surgery in breast cancer patients
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Author
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Abstract
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| Currently, there are no markers to identify patients with liver-only or liver-dominant metastases that would benefit from hepatic surgery. Here we characterized histopathological growth patterns (HGPs) of liver metastases in a consecutive series of 36 breast cancer patients who underwent hepatic surgery. Survival analyses showed that the presence of a desmoplastic HGP in the liver metastases (a rim of fibrous tissue separating cancer cells from the liver parenchyma, present in 20 (56%) patients) is independently associated with favorable progression-free and overall survival when compared with the replacement HGP (cancer cells growing into the liver parenchyma, present in 16 (44%) patients). |
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Language
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English
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Source (journal)
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NPJ breast cancer. - New York, NY, 2015, currens
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Publication
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New York, NY
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Breast Cancer Research Foundation
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2020
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ISSN
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2374-4677
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DOI
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10.1038/S41523-020-00209-1
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Volume/pages
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6
:1
(2020)
, 5 p.
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Article Reference
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64
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ISI
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000600109900001
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Pubmed ID
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33339824
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Medium
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E-only publicatie
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Full text (Publisher's DOI)
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Full text (open access)
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