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Title
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A flare for the unexpected : bone flare as response to tyrosine kinase inhibitor treatment in a lung cancer patient: new osteoblastic bone lesions in a lung cancer patient may represent bone flare and should not be misdiagnosed as disease progression
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Author
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Abstract
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| We report the case of a 72-year-old female never-smoker with stage IV endothelial growth factor-receptor (EGFR) mutated lung adenocarcinoma. This patient was started on first line tyrosine kinase-inhibitor (TKI) and seemingly developed new bone metastases under this treatment. As there was a-remarkable-discrepancy between the partial response seen in the primary tumor and non-osseous-metastatic-locations, the possibility of a bone flare phenomenon was considered. In this case report, we demonstrate that new bony lesions are not always synonymous with disease progression. |
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Language
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English
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Source (journal)
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Journal of the Belgian Society of Radiology / Belgian Society of Radiology
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Publication
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Ubiquity Press
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2020
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ISSN
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2514-8281
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DOI
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10.5334/JBSR.1907
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Volume/pages
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104
:1
(2020)
, 4 p.
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Article Reference
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18
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ISI
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000605447600002
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Pubmed ID
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32377620
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Medium
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E-only publicatie
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Full text (Publisher's DOI)
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Full text (open access)
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