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Title
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Type 1 diabetes and epilepsy : an intriguing link
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Author
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Abstract
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| The link between epilepsy and type 1 diabetes has been underappreciated. The prevalence of epilepsy in type 1 diabetic patients is higher than in the general population. Prevalence varies among different studies, but a two- to sixfold increase compared to the general population is reported. Patients with type 1 diabetes and epilepsy often develop epilepsy before adolescence and have different types of seizures. Temporal lobe epilepsy and idiopathic generalized epilepsy are the most frequently reported epilepsy syndromes. The factors underlying this association remain to be elucidated, but metabolic, cerebrovascular, autoimmune and genetic factors are suggested to contribute. This review gives an overview of existing literature, starting from an illustrative case report. Future research in patient characteristics and etiological factors is needed. Understanding the genetics of these two diseases seems necessary to gain more insight in this intriguing link. |
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Language
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English
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Publication
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2020
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Volume/pages
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22
:1
(2020)
, p. 12-15
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Full text (publisher's version - intranet only)
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