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Title
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Coping strategy influences quality of life in patients with advanced lung cancer by mediating mood
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Author
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Abstract
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| Patients with advanced lung cancer and depressive/anxiety symptoms experience worse quality of life (QoL) We examined whether and how coping strategy influenced QoL in these patients. A multicenter cross-sectional study of 125 patients with advanced lung cancer was conducted. Patients using positive reframing as coping strategy, experience less anxiety and depressive symptoms leading to a better QoL. Introduction: Patients with advanced lung cancer experience high physical symptom burden with substantial psychological distress. Depressive and anxiety symptoms are common and associated with worse quality of life (QoL). Early palliative care (EPC) addresses the complex supportive care needs improving QoL and mood. The mechanisms of EPC are uncertain. We examined whether and how coping strategy, a primary component of EPC, influenced QoL in these patients. Materials and Methods: We conducted a multicenter cross-sectional study of patients with advanced lung cancer. A total of 125 patients completed assessments of QoL (QLQ-C15-PAL), depressive and anxiety symptoms (HADS), and coping (brief COPE questionnaire). The data were analyzed by descriptive statistics. To determine whether and how coping strategy influences QoL, correlations and logistic regressions were performed. Results: Positive refraining correlates significantly with global QoL (r 0.25, P <.01), emotional well-being (r= 0.33, P <.01), pain (r = 0.30, P <.01), fatigue (r = 0.22, P <.01), loss of appetite (r = 0.22, P <.01) and nausea (r = 0.24, P <.01). Self-blame correlates significantly with worse emotional well-being (r = 0.19, P <.05) and insomnia (r = 0.19, P <.05). Using a 4-step logistic regression model, it was found that anxiety and depressive symptoms fully mediated the relationship between positive reframing and QoL. Conclusions: Patients with advanced lung cancer using positive refraining as coping strategy, experience higher QoL. The mechanism behind it seems that positive reframing goes along with less anxiety and depressive symptoms leading to a better QoL. Self-blame leads to more insomnia and worse emotional well-being. Providing skills to cope effectively could impact QoL in these patients. |
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Language
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English
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Source (journal)
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Clinical lung cancer
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Publication
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2021
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ISSN
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1525-7304
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DOI
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10.1016/J.CLLC.2020.09.010
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Volume/pages
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22
:2
(2021)
, p. 146-152
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ISI
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000632897400011
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Pubmed ID
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33060059
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Full text (Publisher's DOI)
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Full text (open access)
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Full text (publisher's version - intranet only)
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