Publication
Title
Parenchymal-sparing hepatectomy with hepatic vein resection and reconstruction
Author
Abstract
Background Hepatectomy remains the most important treatment modality for most malignant liver tumors. Vascular involvement stays a reason for unresectability or major parenchymal resection. A possible way to avoid this is parenchymal-sparing hepatectomy (PSHX) with vascular resection and reconstruction (HVRR). In this article, we aim to demonstrate the specific role of this technique in avoiding post-hepatectomy liver failure (PHLF). Methods A retrospective analysis of 10 patients who underwent HVRR was conducted. (99m)Technetium-mebrofenin hepatobiliary scintigraphy (HBS) was used to predict the future liver remnant function (FLRF). Calculations were made for each patient to compare HVRR and major hepatectomy (with or without portal vein embolization). Results In our cohort, there was no perioperative mortality. Two patients suffered a Clavien-Dindo grade 3a complication and none had clinically significant PHLF. Estimated FLRF was significantly higher in HVRR compared to major hepatectomy after portal vein embolization (p < .005). Conclusions Instead of focusing on inducing liver remnant hypertrophy, preserving parenchyma through HVRR can be an interesting treatment strategy. It can be performed with an acceptable operative risk. Calculations of FLRF (using HBS) suggest that this approach is able to reduce the risk for PHLF and related morbidity or mortality.
Language
English
Source (journal)
Acta chirurgica Belgica. - Brussel, 1946 - 1996
Publication
Abingdon : Taylor & francis ltd , 2022
ISSN
0001-5458
DOI
10.1080/00015458.2021.1915021
Volume/pages
122 :5 (2022) , p. 334-340
ISI
000656334800001
Pubmed ID
33860723
Full text (Publisher's DOI)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identifier
Creation 28.06.2021
Last edited 25.02.2025
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