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Title
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Quality appraisal of antibiotic consumption in the community, European Union/European Economic Area, 2009 and 2017
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Author
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Institution/Organisation
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ESAC-Net Study Group
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Abstract
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| Objectives: The quality of antibiotic consumption in the community can be assessed using 12 drug-specific quality indicators (DSQIs) developed by the European Surveillance of Antimicrobial Consumption (ESAC) project. We compared quality in 2009 and 2017 in the EU/European Economic Area (EEA) and evaluated the impact of using different DDD values (ATC/DDD indices 2011 and 2019) for the 2009 quality assessment using these DSQIs and a joint scientific opinion (JSO) indicator. Methods: We calculated the 12 DSQIs and the JSO indicator for 2017 and for 2009 for EU/EEA countries able to deliver values. For each of the indicators we grouped the 2017 and 2009 indicator values into four quartiles. To evaluate changes in quality between 2009 and 2017, we used the quartile distribution of the 2009 indicator values in 30 EU/EEA countries as benchmarks. In addition, we compared the quality assessment for 2009 using the ATC/DDD indices 2011 and 2019. Results: In 2017, a difference in the quality of antibiotic consumption in the community between northern and southern EU/EEA countries remained, but also several eastern EU/EEA countries shifted towards lower quality. Quality of antibiotic consumption decreased between 2009 and 2017 in particular indicator values for penicillin, quinolone, relative b-lactam and broad- versus narrow-spectrum antibiotic consumption, and seasonal variation. Using different ATC/DDD indices did not substantially change countries’ ranking based on their DSQI values. Conclusions: The quality of antibiotic consumption in the community as measured by the DSQIs further decreased between 2009 and 2017, especially in Southern and Eastern European countries. A continuous effort to improve antibiotic consumption is essential to reduce antibiotic consumption in general and the use of broadspectrumantibiotics in particular. |
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Language
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English
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Source (journal)
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The journal of antimicrobial chemotherapy. - London, 1975, currens
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Publication
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London
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2021
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ISSN
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0305-7453
[print]
1460-2091
[online]
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DOI
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10.1093/JAC/DKAB178
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Volume/pages
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76
:S2
(2021)
, p. 60-67
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ISI
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000684146500009
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Pubmed ID
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34312656
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Full text (Publisher's DOI)
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Full text (open access)
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