Title
|
|
|
|
The use of methotrexate in conservative treatment of placenta accreta spectrum disorders
|
|
Author
|
|
|
|
|
|
Abstract
|
|
|
|
Aim of the study: This article reports on a series of patients with placenta accreta spectrum (PAS) disorder who were treated conservatively with Methotrexate (MTX) administration with or without embolization. We investigate whether there is a place for MTX in conservative treatment of PAS. Methods: We present a single-center retrospective case series of five patients. In all patients, diagnosis was unexpected and not made prenatally. Conclusion: The benefits should be weighed against the possible drug toxicity. Today high-quality evidence is lacking. PAS covers a broad spectrum of pathology, standardization in prenatal and postnatal diagnosis can help to compare evidence on treatment. |
|
|
Language
|
|
|
|
English
|
|
Source (journal)
|
|
|
|
The journal of maternal-fetal and neonatal medicine. - New York, N.Y., 2005, currens
|
|
Publication
|
|
|
|
Abingdon
:
Taylor & francis ltd
,
2022
|
|
ISSN
|
|
|
|
1476-7058
|
|
DOI
|
|
|
|
10.1080/14767058.2021.1951211
|
|
Volume/pages
|
|
|
|
35
:25
(2022)
, p. 7514-7517
|
|
ISI
|
|
|
|
000674860300001
|
|
Pubmed ID
|
|
|
|
34278931
|
|
Full text (Publisher's DOI)
|
|
|
|
|
|