Accelerated partial breast irradiation : current status with a focus on clinical practice

Miranda, Fabiana A.; Teixeira, Lorine A.B.; Heinzen, Rebeca N.; de Andrade, Felipe Eduardo M.; Hijal, Tarek; Buchholz, Thomas A.; Moraes, Fabio Y.; Poortmans, Philip; Marta, Gustavo N.

doi:10.1111/TBJ.13164

Title

Accelerated partial breast irradiation : current status with a focus on clinical practice

Author

Miranda, Fabiana A.

Teixeira, Lorine A.B.

Heinzen, Rebeca N.

de Andrade, Felipe Eduardo M.

Hijal, Tarek

Buchholz, Thomas A.

Moraes, Fabio Y.

Poortmans, Philip

Marta, Gustavo N.

Abstract

Accelerated partial breast irradiation (APBI), a radiation technique in which only the tumor bed is treated, has now become an acceptable radiation modality for selected early-stage breast cancer patients. Compared to conventional whole breast irradiation (WBI), APBI has some benefits with regard to the reduced total irradiated breast volume and the shorter treatment time. The role of APBI, which can be delivered using diverse techniques, has been evaluated in several prospective randomized phase III trials. These clinical trials demonstrate diverging outcomes relating to local recurrence, while establishing comparable effect in terms of survival between APBI with WBI. The aim of this study was to review the current status of APBI with a focus on clinical practice.

Language

English

Source (journal)

Breast journal. - Oxford

Publication

Oxford : 2019

ISSN

1075-122X [print]

1524-4741 [online]

DOI

10.1111/TBJ.13164

Volume/pages