Detection of local recurrence following breast-conserving treatment in young women with early breast cancer : optimization of long-term follow-up strategies

van der Sangen, Maurice J.C.; Scheepers, Sanne W.M.; Poortmans, Philip M.P.; Luiten, Ernest J.T.; Nieuwenhuijzen, Grard A.P.; Voogd, Adri C.

doi:10.1016/J.BREAST.2012.08.006

Title

Detection of local recurrence following breast-conserving treatment in young women with early breast cancer : optimization of long-term follow-up strategies

Author

van der Sangen, Maurice J.C.

Scheepers, Sanne W.M.

Poortmans, Philip M.P.

Luiten, Ernest J.T.

Nieuwenhuijzen, Grard A.P.

Voogd, Adri C.

Abstract

The detection of a local recurrence (LR) in young women with breast cancer after breast-conserving treatment (BCT) was investigated to compare the impact of different long-term follow-up strategies. Between 1988 and 2005, 937 women aged <= 40 years were treated with BCT for early-stage breast cancer in the southern part of the Netherlands. Up to October 2009, 152 had developed an isolated LR. Information on follow-up visits was available for 124 of them. Fifty-four LRs (44%) were diagnosed within 5 years and 70 (56%) more than 5 years after BCT. Fifty-six LRs (45%) were detected during routine follow-up visits and 68 (55%) presented between two visits. Sixty-six LRs (53%) were diagnosed in patients reporting symptoms. In 31 patients (25%) the LR was found by mammography alone. About a quarter of the LRs was larger than 2 cm in diameter. These results imply that current follow-up strategies for young women with BCT do not guarantee a timely detection of LR. (C) 2012 Elsevier Ltd. All rights reserved.

Language

English

Source (journal)

The Breast. - Edinburgh

Publication

Edinburgh : 2013

ISSN

0960-9776

DOI

10.1016/J.BREAST.2012.08.006

Volume/pages

22 :3 (2013) , p. 351-356