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Title
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Epigenetic biomarkers of radiation-induced cardiovascular disease and secondary cancers
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Author
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Abstract
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| Ionizing radiation (IR) is routinely used in diagnosis and therapy. However, incidental radiation exposure of out-of-target tissues and organs may lead to long-term radiation-induced adverse effects including radiation-induced cardiovascular disease (RICVD) and secondary cancers. Investigating the underlying biological mechanisms involved in RICVD and secondary cancers can contribute to the discovery of disease-specific biomarkers. These biomarkers can help identify at-risk patients before they develop pathological symptoms thereby tackling a primary clinical concern. Consequently, the aim of this PhD is to investigate epigenetic biomarkers for two IR delayed effects; RICVD and glioblastoma as a possible secondary cancer to IR. |
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Language
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English
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Publication
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Antwerp
:
University of Antwerp, Faculty of Medicine and Health Sciences
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2023
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Volume/pages
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IV, V, 224 p.
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Note
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Guns, Pieter-Jan [Supervisor]
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Rafi, Benotmane [Supervisor]
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Ramadan, Raghda [Supervisor]
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Aerts, An [Supervisor]
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Full text (open access)
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