Publication
Title
Designing clinical trials based on modern imaging and metastasis-directed treatments in patients with oligometastatic breast cancer : a consensus recommendation from the EORTC Imaging and Breast Cancer Groups
Author
Abstract
Breast cancer remains the most common cause of cancer death among women. Despite its considerable histological and molecular heterogeneity, those characteristics are not distinguished in most definitions of oligometastatic disease and clinical trials of oligometastatic breast cancer. After an exhaustive review of the literature covering all aspects of oligometastatic breast cancer, 35 experts from the European Organisation for Research and Treatment of Cancer Imaging and Breast Cancer Groups elaborated a Delphi questionnaire aimed at offering consensus recommendations, including oligometastatic breast cancer definition, optimal diagnostic pathways, and clinical trials required to evaluate the effect of diagnostic imaging strategies and metastasis-directed therapies. The main recommendations are the introduction of modern imaging methods in metastatic screening for an earlier diagnosis of oligometastatic breast cancer and the development of prospective trials also considering the histological and molecular complexity of breast cancer. Strategies for the randomisation of imaging methods and therapeutic approaches in different subsets of patients are also addressed.
Language
English
Source (journal)
The lancet oncology. - London
Publication
New york : Elsevier science inc , 2023
ISSN
1470-2045
DOI
10.1016/S1470-2045(23)00286-3
Volume/pages
24 :8 (2023) , p. E331-E343
ISI
001055272400001
Pubmed ID
37541279
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identifier
Creation 30.10.2023
Last edited 07.12.2023
To cite this reference