Publication
Title
Correlation between abdominal wall stimulation and spinal cord stimulator tip location : a nonrandomized clinical trial
Author
Abstract
Objectives: This study aimed to investigate the correlation between the vertebral level of paddle placement and abdominal wall stimulation (AWS) after differential target multiplexed spinal cord stimulation (SCS) to improve the safety and effectiveness of SCS for patients with chronic pain, particularly those with low back pain (LBP).Materials and Methods: The Correlation Between Abdominal Wall Stimulation and Spinal Cord Stimulator Tip Location study was a nonrandomized clinical trial that included 24 patients with SCS for persistent spinal pain syndrome (PSPS) type 2 (trial ID: NCT05565469). The intervention involved increasing stimulation amplitude to a maximum tolerable value and obtaining numerical rating scores for AWS. The primary outcome measure was the association between AWS, the neurostimulator tip, and conus medullaris location, whereas the secondary outcome was the pre-postinterventional difference in proportion of patients experiencing AWS. Patient demographics and postoperative imaging were assessed. Statistical analyses involved descriptive statistics, a descriptive logistic regression, and a McNemar test.Results: The results of the study showed that seven (29%) of the 24 patients experienced AWS either previously or during interventional stimulation. However, there was no significant correlation found between AWS and the location of the neuro-stimulator tip or conus medullaris, and there was no difference in the pre-postinterventional proportion of patients experiencing AWS.Conclusions: The study concludes that a relatively high proportion of patients who received SCS for PSPS type 2 experienced or previously experienced AWS. There was no significant correlation found between the location of the neurostimulator tip and the occurrence of AWS. This suggests that AWS may not be solely dependent on the stimulation itself and emphasizes the need to consider other factors. Nonetheless, this study provides important insights into the occurrence of AWS in patients receiving SCS for PSPS type 2 and highlights the need for further research in this area.Clinical Trial Registration: The Clinicaltrials.gov registration number for the study is NCT05565469.
Language
English
Source (journal)
Neuromodulation. - Oxford, 1998, currens
Publication
Oxford : 2023
ISSN
1094-7159 [Print]
1525-1403 [Online]
DOI
10.1016/J.NEUROM.2023.07.004
Volume/pages
26 :7 (2023) , p. 1459-1464
ISI
001088315400001
Pubmed ID
37632515
Full text (Publisher's DOI)
Full text (open access)
The author-created version that incorporates referee comments and is the accepted for publication version Available from 04.04.2024
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
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Affiliation
Publications with a UAntwerp address
External links
Web of Science
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Creation 04.12.2023
Last edited 12.12.2023
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