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Title
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Evaluating the predictive value of a short preoperative holistic risk factor screening questionnaire in preventing persistent pain in elective adult surgery : study protocol for a prospective observational pragmatic trial [PERISCOPE]
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Author
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Abstract
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| Background: The global incidence of persistent pain after surgery is approximately 10%, with considerable clinical and socio-economic impacts. Despite identifying many risk factors in its development and the challenging management of the often neuropathic pain complaints, preoperative recognition of high-risk patients in various surgical populations using a standardized risk factor assessment questionnaire is lacking. This study evaluates the predictive value of a short holistic risk factor screening questionnaire as a first step in preventing and treating persistent pain in adults undergoing elective surgery.Methods: This prospective observational pragmatic trial will include 560 adults undergoing elective surgery. The primary endpoint is the evaluation of the predictive value of the screening questionnaire, including the optimal cut-off determination in terms of sensitivity and specificity for inclusion in a perioperative high-vigilance program. Secondary endpoints are postoperative pain (intensity and characterization using the NRS and DN4), postoperative analgesic usage, and well-being using the EQ-5D-5 L. To assess the performance of the designed screening questionnaire in the identification of psychosocial pain aspects, HADs, and STAI-trait are being surveyed. Additionally, the multidimensional pain inventory (MPI, part 1) is being used to assess the impact of pain on daily life in patients.Discussion: This pragmatic clinical trial will evaluate a short preoperative screening questionnaire to predict persistent postoperative pain after elective surgery in adults. Suppose high-risk patients could be identified earlier using this short preoperative holistic screening questionnaire. In that case, it might contribute to a more widespread implementation of standardized preoperative assessment and awareness for preventing persistent postoperative pain. |
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Language
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English
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Source (journal)
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Journal of pain research
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Publication
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2023
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ISSN
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1178-7090
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DOI
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10.2147/JPR.S439824
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Volume/pages
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16
(2023)
, p. 4281-4287
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ISI
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001125013600001
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Pubmed ID
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38107366
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Full text (Publisher's DOI)
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Full text (open access)
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