Publication
Title
Stimulation crosstalk between cochlear and vestibular spaces during cochlear electrical stimulation
Author
Abstract
ObjectivesPossible beneficial "crosstalk" during cochlear implant stimulation on otolith end organs has been hypothesized. The aim of this case-control study is to analyze the effect of electrical cochlear stimulation on the vestibule (otolith end-organ), when using a cochleo-vestibular implant, comparing vestibular stimulation (VI) and cochlear stimulation (CI).MethodsFour patients with bilateral vestibulopathy were included. A double electrode array research implant was implanted in all cases. Dynamic Gait Index (DGI), VOR gain measured by using vestibular head impulse test (vHIT), acoustic cervical myogenic responses (cVEMP) recordings, and electrical cVEMP were used in all cases. Trans-impedance Matrix (TIM) analysis was used to evaluate the current flow from the cochlea to the vestibule.ResultsWhile patients did not have any clinical vestibular improvement with the CI stimulation alone, gait metrics of the patients revealed improvement when the vestibular electrode was stimulated. The average improvement in the DGI was 38% when the vestibular implant was activated, returning to the normal range in all cases. Our findings suggest that any current flow from the cochlear space to the otolith organs was insufficient for effective cross-stimulation. The functional results correlated with the data obtained in TIM analysis, confirming that there is no current flow from the cochlea to the vestibule.ConclusionThe only way to produce effective electrical otolith end-organ stimulation, demonstrated with this research implant, is by direct electrical stimulation of the otolith end organs. No effective cross-stimulation was found from cochlear electrode stimulation.Level of Evidence4 Laryngoscope, 2023 We analyze in this research the possible beneficial "crosstalk" during cochlear implant stimulation on otolith end organs has been hypothesized. The aim of this study is to analyze the effect of electrical cochlear stimulation on the vestibule (otolith end organ), when using a cochleo-vestibular implant.image
Language
English
Source (journal)
The laryngoscope / American Laryngological, Rhinological and Otological Society. - St.Louis, Mo., 1896, currens
Publication
Hoboken : Wiley , 2023
ISSN
0023-852X [print]
1531-4995 [online]
DOI
10.1002/LARY.31174
Volume/pages
(2023) , p. 1-7
ISI
001120907200001
Pubmed ID
38010817
Full text (Publisher's DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identifier
Creation 09.01.2024
Last edited 12.01.2024
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