|
Title
|
|
|
|
Evaluation of methods measuring medication adherence in patients with polypharmacy : a longitudinal and patient perspective
|
|
|
Author
|
|
|
|
|
|
|
Abstract
|
|
|
|
| Purpose To explore patients’ willingness to have medication adherence measured using different methods and evaluate the feasibility and validity of their combination (i.e., pill counts, a medication diary and a questionnaire assessing adherence two months post-discharge). Methods (1) A cross-sectional evaluation of the willingness of patients with polypharmacy to have their medication adherence measured post-discharge. (2) Medication adherence was monitored during two months using pill counts based on preserved medication packages and a diary in which patients registered their adherence-related problems. During a home visit, the Probabilistic Medication Adherence Scale (ProMAS) and a questionnaire on feasibility were administered. Results A total of 144 participants completed the questionnaire at discharge. The majority was willing to communicate truthfully about their adherence (97%) and to share adherence-related information with healthcare providers (99%). More participants were willing to preserve medication packages (76%) than to complete a medication diary (67%) during two months. Most participants reported that preserving medication packages (91%), completing the diary (99%) and the ProMAS (99%) were no effort to them. According to the majority of participants (60%), pill counts most accurately reflected medication adherence, followed by the diary (39%) and ProMAS (1%). Medication adherence measured by pill counts correlated significantly with ProMAS scores, but not with the number of diary-reported problems. However, adherence measured by the medication diary and ProMAS correlated significantly. Conclusion Combining tools for measuring adherence seems feasible and can provide insight into the accordance of patients’ actual medication use with their prescribed regimen, but also into problems contributing to non-adherence. |
|
|
|
Language
|
|
|
|
English
|
|
|
Source (journal)
|
|
|
|
European journal of clinical pharmacology. - Heidelberg, 1970, currens
|
|
|
Publication
|
|
|
|
Heidelberg
:
Springer
,
2024
|
|
|
ISSN
|
|
|
|
0031-6970
[print]
1432-1041
[online]
|
|
|
DOI
|
|
|
|
10.1007/S00228-024-03661-1
|
|
|
Volume/pages
|
|
|
|
80
:6
(2024)
, p. 891-900
|
|
|
ISI
|
|
|
|
001172893700001
|
|
|
Pubmed ID
|
|
|
|
38427083
|
|
|
Full text (Publisher's DOI)
|
|
|
|
|
|
|
Full text (open access)
|
|
|
|
|
The author-created version that incorporates referee comments and is the accepted for publication version Available from 01.09.2024
|
|
|
|
Full text (publisher's version - intranet only)
|
|
|
|
|
|