Publication
Title
Comprehensive mapping of the AOP-Wiki database : identifying biological and disease gaps
Author
Abstract
Introduction: The Adverse Outcome Pathway (AOP) concept facilitates rapid hazard assessment for human health risks. AOPs are constantly evolving, their number is growing, and they are referenced in the AOP-Wiki database, which is supported by the OECD. Here, we present a study that aims at identifying well-defined biological areas, as well as gaps within the AOP-Wiki for future research needs. It does not intend to provide a systematic and comprehensive summary of the available literature on AOPs but summarizes and maps biological knowledge and diseases represented by the already developed AOPs (with OECD endorsed status or under validation).
Language
English
Source (journal)
Frontiers in toxicology
Publication
2024
DOI
10.3389/FTOX.2024.1285768
Volume/pages
6 (2024) , p. 1-22
Article Reference
1285768
Full text (Publisher's DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Record
Identifier
Creation 11.03.2024
Last edited 12.03.2024
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