Publication
Title
Hereditary motor neuropathy
Author
Abstract
Hereditary motor neuropathy (HMN) is an enigmatic group of disorders. The classical presentation is early onset of distal weakness and muscular atrophy commonly complicated by foot deformities without clinical or electrophysiological evidence of sensory involvement. The arbitrary boundaries set up by the classifications and distinctions with other inherited neuro(no)pathies are increasingly crossed and appear less applicable in daily practice due to the rapid increase in the identification of genetic causes. Nevertheless, 50%–70% of cases remain genetically unsolved. This chapter discusses the clinical evaluation, genetic heterogeneity (41 genes), pathomechanisms and recent scientific advances.
Language
English
Source (book)
Reference module in neuroscience and biobehavioral psychology
Publication
2024
ISBN
978-0-323-95702-1
978-0-12-809324-5
DOI
10.1016/B978-0-323-95702-1.00083-X
Volume/pages
p. 1-15
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Record
Identifier
Creation 21.03.2024
Last edited 26.03.2024
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