Publication
Title
Acellular aragonite-based scaffold for the treatment of joint surface lesions of the knee : a minimum 5-year follow-up study
Author
Abstract
Objective A novel aragonite-based scaffold has been developed. In this study, mid-term clinical and magnetic resonance imaging (MRI) results on 12 patients affected by isolated chondral or osteochondral lesions of the knee treated by the scaffold implantation have been evaluated at a mean follow-up of 6.5 (range: 5-8) years.Design The study population consisted of 3 females and 9 males, mean age 34.4 (20-51) years. The lesion was located on the medial femoral condyle, the trochlea, and the lateral femoral condyle in 5, 5, and 2 patients, respectively. In all cases, a single lesion over grade 3 of the International Cartilage Restoration and Joint Preservation Society (ICRS) classification was treated: in 9 cases by implantation of one plug, and in 2 cases with 2 plugs; the mean size of the lesion was 2.5 cm2 (1-7).Results One patient failed and was revised with a custom-made metal implant (Episealer). Overall, Knee Injury and Osteoarthritis Outcome Score (KOOS) significantly improved from 45 +/- 13 preoperatively to 86 +/- 13 at final follow-up. All KOOS subscales improved significantly: pain subscale increased from 48 +/- 12 to 92 +/- 11; symptoms from 66 +/- 13 to 91 +/- 13; activity of daily living (ADL) from 60 +/- 19 to 90 +/- 21; sport from 23 +/- 20 to 75 +/- 20; finally, quality of life (QoL) increased from 27 +/- 14 to 77 +/- 19. Long-term MRI MOCART score was 64.Conclusions This study shows continued significant clinical improvement and good magnetic resonance imaging (MRI) findings with a minimum 5 years follow-up after implantation of a novel aragonite derived scaffold for the treatment of cartilage lesions of the knee. One patient failed and was revised with a custom-made metal implant (Episealer).
Language
English
Source (journal)
Cartilage. - -
Publication
Thousand oaks : Sage publications inc , 2024
ISSN
1947-6035
1947-6043
DOI
10.1177/19476035241227346
Volume/pages
(2024) , 8 p.
ISI
001178408900001
Full text (Publisher's DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identifier
Creation 29.03.2024
Last edited 09.04.2024
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