Publication
Title
Atrial and ventricular strain using cardiovascular magnetic resonance in the prediction of outcomes of pericarditis patients : a pilot study
Author
Abstract
ObjectiveOur study aimed to explore with cardiovascular magnetic resonance (CMR) the impact of left atrial (LA) and left ventricular (LV) myocardial strain in patients with acute pericarditis and to investigate their possible prognostic significance in adverse outcomes.MethodThis retrospective study performed CMR scans in 36 consecutive patients with acute pericarditis (24 males, age 52 [23-52]). The primary endpoint was the combination of recurrent pericarditis, constrictive pericarditis, and surgery for pericardial diseases defined as pericardial events. Atrial and ventricular strain function were performed on conventional cine SSFP sequences.ResultsAfter a median follow-up time of 16 months (interquartile range [13-24]), 12 patients with acute pericarditis reached the primary endpoint. In multivariable Cox regression analysis, LA reservoir and LA conduit strain parameters were all independent determinants of adverse pericardial diseases. Conversely, LV myocardial strain parameters did not remain an independent predictor of outcome. With receiving operating characteristics curve analysis, LA conduit and reservoir strain showed excellent predictive performance (area under the curve of 0.914 and 0.895, respectively) for outcome prediction at 12 months.ConclusionLA reservoir and conduit mechanisms on CMR are independently associated with a higher risk of adverse pericardial events. Including atrial strain parameters in the management of acute pericarditis may improve risk stratification.Clinical relevance statementAtrial strain could be a suitable non-invasive and non-contrast cardiovascular magnetic resonance parameter for predicting adverse pericardial complications in patients with acute pericarditis.Key Points center dot Myocardial strain is a well-validated CMR parameter for risk stratification in cardiovascular diseases.center dot LA reservoir and conduit functions are significantly associated with adverse pericardial events.center dot Atrial strain may serve as an additional non-contrast CMR parameter for stratifying patients with acute pericarditis.Key Points center dot Myocardial strain is a well-validated CMR parameter for risk stratification in cardiovascular diseases.center dot LA reservoir and conduit functions are significantly associated with adverse pericardial events.center dot Atrial strain may serve as an additional non-contrast CMR parameter for stratifying patients with acute pericarditis.Key Points center dot Myocardial strain is a well-validated CMR parameter for risk stratification in cardiovascular diseases.center dot LA reservoir and conduit functions are significantly associated with adverse pericardial events.center dot Atrial strain may serve as an additional non-contrast CMR parameter for stratifying patients with acute pericarditis.
Language
English
Source (journal)
European radiology. - Secaucus, N.J., 1991, currens
Publication
New york : Springer , 2024
ISSN
0938-7994 [print]
1432-1084 [online]
DOI
10.1007/S00330-024-10677-9
Volume/pages
(2024) , 12 p.
ISI
001180331300001
Pubmed ID
38467940
Full text (Publisher's DOI)
Full text (open access)
UAntwerpen
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Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
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Creation 29.03.2024
Last edited 05.04.2024
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