Publication
Title
Angiogenic properties of mesenchymal stem cells in a mouse model of limb ischemia
Author
Abstract
Mesenchymal stem cells (MSCs) can be obtained from adult bone marrow and adipose tissue in large quantities and are the main cell types that contribute to recovery from ischemia because, among their biological activities, they produce several proangiogenic paracrine factors and differentiate into endothelial cells. Mouse hind limb ischemia induced by surgery is a useful animal model to study the angiogenic properties of MSCs, but it requires several precautions to be reproducible. The preparation of MSCs, the ischemic surgery, and the physiological and histological analyses are described in detail.
Language
English
Source (journal)
Methods in molecular biology. - Totowa, N.J., 1984, currens
Source (book)
Animal models for stem cell therapy / Christ, Bruno [edit.]; et al. [edit.]
Publication
New York, N.Y. : Humana Press , 2014
ISSN
1064-3745 [print]
1940-6029 [electronic]
ISBN
978-1-4939-1452-4
978-1-4939-1453-1
DOI
10.1007/978-1-4939-1453-1_13
Volume/pages
1213 , p. 147-169
Full text (Publisher's DOI)
UAntwerpen
Publication type
Subject
External links
Record
Identifier
Creation 10.04.2024
Last edited 10.04.2024
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