Publication
Title
Clinical characteristics and outcomes among hospitalised COVID-19 patients across epidemic waves in Spain : an unCoVer analysis = Características clínicas y resultados entre los pacientes hospitalizados por COVID-19 a lo largo de las oleadas epidémicas en España : unCoVer análisis
Author
Abstract
Background and objectives The COVID-19 pandemic had a significant impact in population health worldwide, and particularly in people with pre-existing chronic diseases. Early risk identification and stratification is essential to reduce the impact of future outbreaks of pandemic potential. This study aimed to comprehensively examine factors associated with COVID-19 mortality across the pandemic waves in Spain. Methods A retrospective study analyzed the characteristics of 13,974 patients admitted to Spanish hospitals due to SARS-CoV-2 infection from 2020-01-28 to 2022-12-31. The demographic and clinical features of patients during hospitalization on each pandemic waves were analyzed. Main findings The findings highlight the heterogeneity of patient characteristics, comorbidities and outcomes, across the waves. The high prevalence of cardiometabolic diseases (53.9%) among COVID-19 patients emphasizes the importance of controlling these risk factors to prevent severe COVID-19 outcomes. Conclusions In summary, the study associate hospital mortality with factors such as advanced age and comorbidities. The decline in mortality after the 4th wave indicates potential influences like vaccination, viral adaptation, or improved treatments. Notably, dementia and cancer metastases emerge as critical factors linked to higher mortality, highlighting the importance of addressing these conditions in COVID-19 management and preparing for future challenges.
Language
English, Spanish
Source (journal)
Medicina clinica, organo de la Facultad de Medicina, Hospitales y Sociedades Medicas de Barcelona / Universidad de Barcelona. Facultad de Medicina. - Barcelona
Publication
Barcelona : 2024
ISSN
0025-7753
DOI
10.1016/J.MEDCLI.2023.12.030
Volume/pages
162 :11 (2024) , p. 523-531
ISI
001249936200003
Pubmed ID
38555273
Full text (Publisher's DOI)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Record
Identifier
Creation 22.04.2024
Last edited 03.07.2024
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