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Title
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Determination of selected POPs in human serum by solid-phase disk extraction and dual-column capillary gas chromatography with electron capture detection
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Author
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Abstract
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| An improved clean-up method by solid-phase disk extraction was developed to isolate and concentrate trace levels of POPs (persistent organochlorine pollutants) in human serum prior to gas chromatography with electron capture detection on two different capillary columns, providing an improved selectivity. An Empore(TM) C-18 bonded silica extraction disk cartridge is used for the initial extraction and enrichment of the analytes. Subsequent clean-up is achieved by concentrated sulphuric acid and silica gel adsorption chromatography, Recoveries for selected POPs are ranging from 62 to 74% and a good reproducibility (RSD < 14%) is demonstrated. Human samples analysed under these conditions, show a similar relative concentration profile. |
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Language
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English
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Source (journal)
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International journal of environmental analytical chemistry. - New York, N.Y.
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Publication
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New York, N.Y.
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2000
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ISSN
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0306-7319
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DOI
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10.1080/03067310008034129
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Volume/pages
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76
:3
(2000)
, p. 167-178
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ISI
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000088132300002
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Full text (Publisher's DOI)
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