Publication
Title
Vitamin A abuse : development of cirrhosis despite cessation of vitamin A : a six year clinical and histologic follow-up
Author
Abstract
We report the case of a 35-year-old man who contracted vitamin A-induced liver cirrhosis. Five years before, he had been investigated for vitamin A-induced non-cirrhotic portal hypertension. In this case, the clinical and histopathologic evolution from non-cirrhotic portal hypertension to cirrhosis was documented. In spite of the cessation of pharmaceutical vitamin A intake, the disease progressed. Therapy with colchicine and phenobarbital apparently did not influence evolution to cirrhosis. This suggests that vitamin A can trigger largely unknown mechanisms of liver fibrosis which seem to be self-perpetuating.
Language
English
Source (journal)
Liver. - -
Publication
1992
ISSN
0106-9543
Volume/pages
12 :6 (1992) , p. 381-386
ISI
A1992KF87300004
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identifier
Creation 08.10.2008
Last edited 14.12.2021
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