Publication
Title
Proton relaxation enhancement by means of serum albumine and poly-L-lysine labeled with $DTPA-Gd^{3+}$ : relaxivities as function of molecular weight and conjugation efficiency
Author
Abstract
 A series of poly-L-lysine chains, with molecular weight ranging from 3300 up to 102,000 Da, were labeled with DTPA-Gd3+. No significant differences in longitudinal and transversal relaxivity, could be demonstrated as a function of the chain length. The R1 and R2 relaxivities were respectively 2.5 and 5 times superior to those of plain DTPA-Gd3+ (at 2.4 T). Bovine serum albumin was also labeled in a way that a wide (DTPA-Gd3+)/BSA range (3-39) was obtained. The longitudinal relaxivity, of these paramagnetically labeled albumins, increased with increasing (DTPA-Gd3+)/BSA ratios. This effect was most pronounced at very low (DTPA-Gd3+)/BSA ratios.
Language
English
Source (journal)
Magnetic resonance imaging. - New York
Publication
New York : 1992
ISSN
0730-725X
Volume/pages
10:6(1992), p. 913-917
ISI
A1992JZ77200007
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
 Faculty/Department Research group Publication type Subject Affiliation Publications with a UAntwerp address
External links
 Web of Science
Record
 Identification Creation 08.10.2008 Last edited 20.08.2017 To cite this reference