Title
Statistical mechanics of RNA-folding: a lattice approachStatistical mechanics of RNA-folding: a lattice approach
Author
Faculty/Department
Faculty of Sciences. Physics
Research group
Department of Physics
Publication type
article
Publication
Lancaster, Pa,
Source (journal)
Physical review : E : statistical physics, plasmas, fluids, and related interdisciplinary topics. - Lancaster, Pa, 1993 - 2000
Volume/pages
68(2003), p. 051904,1-8
ISSN
1063-651X
1095-3787
ISI
000187183400041
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Abstract
We propose a lattice model for the secondary structure of RNA based on a self-interacting two-tolerant trail. Self-avoidance and pseudoknots are taken into account. We investigate a simple version of the model in which the native state of RNA consists of just one hairpin. Using exact arguments and Monte Carlo simulations we determine the phase diagram for this case. We show that the denaturation transition is first order and can either occur directly or through an intermediate molten phase.
Full text (open access)
https://repository.uantwerpen.be/docman/irua/957ecc/8095.pdf
E-info
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