Publication
Title
In-vivo research of the thermoregulatory function of the rat studied with magnetic resonance angiography (MRA)
Author
Abstract
In the rat, almost 20% of the total body heat-loss occurs by sympathetically mediated increases in blood flow through a system of arteriovenous anastomoses (AVAs) in the skin of the tail which are absent at the base and abundant at the tip. To study the mechanisms of thermoregulation in the rat tail we monitored online the blood vessel temperature and the arterial and venous vessel size and their mutual vascular volume interactions using in vivo MRA. During a gradual rise in rectal temperature from 36 degrees C to 40 degrees C, tail surface temperatures were measured at ventral (T-a) and lateral (T-v sites overlying the respective vascular bundles. At the base, middle and tip, diameter of the ventral artery and the lateral veins of the heat-loaded animal increased clearly upon rising body temperature. Calculation of (T-a-T-v) in function of the rectal temperature during heating showed that at the tail base (T-a-T-v) was maximum at rectal temperature of 38 degrees C and minimum at 39 degrees C. At the middle and the tip of the tail, a steady rise of (T-a-T-v) was observed. If we assume that vasodilatation is a synchronical process along the length of the tail, then the difference in (T-a-T-v) is due to the presence of AVAs.
Language
English
Source (book)
Medical Imaging 2000: Physiology and Function from Multidimentional Images / Chen, Chin-Tu [edit.]
Publication
s.l. : 2000
ISBN
978-0-8194-3595-8
Volume/pages
p. 466-475
ISI
000087787100048
Full text (Publisher's DOI)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 08.10.2008
Last edited 07.11.2017
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