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Title
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Eosinophilia-myalgia syndrome: a clinicopathological study of four patients
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Author
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Abstract
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| Eosinophilia-myalgia syndrome is an idiopathic disorder characterized by myalgia, especially of the extremities and peripheral eosinophilia. It is found in some patients as a result of tryptophan ingestion. We examined four patients showing clinical features and muscle biopsy changes consistent with eosinophilia-myalgia syndrome. The results of conventional histology were compared with immunohistochemical studies using monoclonal antibodies to human T lymphocytes, macrophages, HLA-DR antigen. Our findings confirm the potential importance of lymphocytes and macrophages in this syndrome. In particular, new observations are presented concerning the immunoreactivity of HLA-DR antigen. |
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Language
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English
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Source (journal)
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Clinical neuropathology. - München
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Publication
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München
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1993
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ISSN
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0722-5091
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Volume/pages
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12
:4
(1993)
, p. 201-210
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ISI
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A1993LQ31000005
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