Hyperelastic warping applied to X-ray micro CT images for the study of human middle ear chain deformations understatic pressure load
Faculty of Sciences. Physics
Singapore :World Scientific, 2007
Middle ear mechanics in research and otology / Eiber, A. [edit.]
University of Antwerp
In everyday life the human ear is subject not only to sound but also to slow, quasi-static pressure variations with amplitudes in the order of tenths of a mm. In the present study we investigated how the ossicular chain deforms and changes its 3-D configuration when acted upon by large static pressures. To determine with good precision the small deformations of the ossicular chain we use 'hyperelastic warping, a deformable image registration method. In this relatively new technique a 3-D finite element model, based on careful segmentation of a template dataset, is deformed until it aligns with a target dataset at a different pressure. 3-D displacement of the ossicles will be shown and expressed mathematically by plotting the displacement of a few landmark points as a function of pressure. We will also describe the 3-D changes in configuration and show how the slippage in the ossicle joints performs as a protecting mechanism of the middle ear.