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Title
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On the construction of an inter-subject diffusion tensor magnetic resonance atlas of the healthy human brain
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Author
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Abstract
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| Voxel based morphometry (VBM) has been increasingly applied to detect diffusion tensor (DT) image abnormalities in patients for different pathologies. An important requisite for a robust VBM analysis is the availability of a high-dimensional non-rigid coregistration technique that is able to align both the spatial and the orientational DT information. Consequently, there is a need for an inter-subject DTI atlas as a group specific reference frame that also contains this orientational DT information. In this work, a population based DTI atlas has been developed that incorporates such orientational DT information with high accuracy and precision. The proposed methodology for constructing such an atlas is compared with a subject based DTI atlas, in which a single subject is selected as the reference image. Our results demonstrate that the population based atlas framework is more accurate with respect to the underlying diffusion information. |
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Language
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English
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Source (journal)
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Neuroimage. - New York
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Publication
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New York
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2008
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ISSN
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1053-8119
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DOI
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10.1016/J.NEUROIMAGE.2008.07.006
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Volume/pages
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43
:1
(2008)
, p. 69-80
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ISI
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000259927400008
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Full text (Publisher's DOI)
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