Title
Plant-derived leading compounds for chemotherapy of human immunodefiency virus (HIV) infection: an update (1998-2007) Plant-derived leading compounds for chemotherapy of human immunodefiency virus (HIV) infection: an update (1998-2007)
Author
Faculty/Department
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences. Pharmacy
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences . Biomedical Sciences
Publication type
article
Publication
Stuttgart ,
Source (journal)
Planta medica: natural products and medicinal plant research. - Stuttgart
Volume/pages
74(2008) :11 , p. 1323-1337
ISSN
0032-0943
ISI
000260174300001
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
The high number of citations of the previous review on anti-HIV compounds from plants published in 1998 in Planta Medica indicates the importance of natural products research in the battle against HIV. Therefore, we have decided to write an update of our previous review paper, this time covering the time span 1998-2007. The following antiviral chemical classes are discussed in detail: alkaloids, carbohydrates, coumarins, flavonoids, lignans, phenolics, proteins, quinones/xanthones, tannins and terpenes. If available, chemical structures, antiviral activity and selectivity, mechanism of action, and structure-activity relationship are presented.
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